艾索（艾迪•墨菲 Eddie Murphy 饰）是底特律黑白两道的大名人，身为警探，却也不时干些偷鸡摸狗的勾当，而且他侦办案件时经常不按程序办事，上司对他十分头痛。这天，艾索因为敲诈烟贩而差点被开除出去，幸亏好运气才免遭于难。　　艾索偶遇了一位刚出狱的好友，这人带着巨额的德国债券来到了底特律。两人重逢后不久，艾索的这位朋友就被谋杀了。深谙此事不简单，艾索开始了调查。他独自一人追踪嫌疑人维克多来到了好莱坞的比佛利山，正当他准备上前盘问时，却被当地警察带回了警局。当艾索调查得悉维多克的确在贩毒时，当地的警长同意介入调查，却将艾索打发回老家。艾索只好劝说当地的一名警员比利（祖德•莱茵霍尔德 Judge Reinhold 饰）和他合作，两人开始了私自调查。Detroit cop Axel Foley is delighted when he receives a surprise visit from his best friend Mikey Tandino, who lives in California. Not long after Mikey arrives in Detroit, Mikey is killed, right in front of Axel, by a man named Zack. Axel follows Zack to Beverly Hills, California, where Beverly Hills police department Lieutenant Andrew Bogomil assigns Detective Billy Rosewood and Rosewood's partner, Sergeant John Taggart, to keep an eye on Axel. Axel visits his friend Jenny Summers, who works in an art gallery. With Jenny's help, Axel discovers that Zack works for Jenny's boss, Victor Maitland, the man who owns the art gallery. Maitland is a drug kingpin who is using the gallery as a front, and Maitland had Zack kill Mikey after Maitland accused Mikey of stealing some of Maitland's bonds. With the help of Jenny, Billy, and Taggart, Axel does what he can to make sure Maitland and Zack won't kill any more people.

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